Which nootropics are best? Known colloquially as “smart drugs,” nootropics are natural or synthetic substances that provide various forms of cognitive enhancement. Some nootropics, like caffeine, are stimulants that many people enjoy every day, while others, like bacopa monnieri, are little-known herbs that are said to improve memory and relieve symptoms of ADHD. There are countless nootropic blends being sold over the counter at pharmacies and health food stores, and many consumers are beginning to incorporate these supplements into their daily health regimens.