Psychedelics have shown great promise in treating a range of mental-health conditions, from PTSD to depression—but they’re not without significant downsides. People who take psychedelics can experience bad trips and unpleasant or dangerous side effects, and the drugs can be time-intensive and arduous to administer. These drugs are “very effective, but they’re scary and they’re chaotic and they’re unpredictable,” says Dillan DiNardo, CEO of psychedelic drug development company Mindstate Design Labs.