Sarah Schmalbruch/INSIDER A stomachache could be just a stomachache or it could be something more serious. We spoke to a few doctors about some of the conditions that could be causing your stomach pain. You could be dealing with irritable bowel syndrome, some kind of food intolerance, or the stomach flu. Other more serious health issues include ovarian cancer, kidney stones, and appendicitis. Your stomach sends you subtle — and not so subtle — signals every day that could point to a potential problem with your health.