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Bookmark or Share- ZMapp - WikipediaZMapp is an experimental biopharmaceutical medication comprising three chimeric monoclonal antibodies under development as a treatment for Ebola virus disease. [1] .
- Molecular Characterization of the Monoclonal Antibodies ...Over the past 3 years, monoclonal antibody (mAb) cocktails have demonstrated high efficacy as treatments against EBOV infection. One such cocktail is ZMAb, which consists of three mouse...
- Antibody-mediated protection against Ebola virus - NatureOne protective cocktail, ZMAb 27,28, contains three mAbs 28: mAb 1H3, which is poorly neutralizing and targets the glycan cap domain of the viral GP that is physically removed from the virion ...
- Molecular Characterization of the Monoclonal Antibodies ...Over the past 3 years, monoclonal antibody (mAb) cocktails have demonstrated high efficacy as treatments against EBOV infection. One such cocktail is ZMAb, which consists of three mouse antibodies, 1H3, 2G4, and 4G7. Here, we present the epitope binding properties of mAbs 1H3, 2G4, and 4G7.
- EBOLA mAbs and Ad-Vectored IFN-a Therapy Rescue Ebola ... - AAASZMAb is a promising treatment against Ebola virus (EBOV) disease that has been shown to protect 50% (two of four) of nonhuman primates (NHPs) when administered 2 days post- infection (dpi). To extend the treatment window and improve protection, we combined ZMAb with adenovirus-vectored interferon-a (Ad-IFN) and evaluated efficacy in EBOV ...
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