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Bookmark or Share- Clinical impact of the implementation of monocyte distribution width ...Background Timely recognition of sepsis in emergency department (ED) is challenging. We evaluated the impact of implementing the biomarker monocyte distribution width (MDW) at bedside, on the time to anti-infective administration. Methods We conducted a before-and-after cohort study in the ED of an academic hospital in Paris, to compare sepsis patients care and outcomes, before and after the ...
- Identification of novel sub-phenotypes of severe ARDS requiring ECMO ...Background Sub-phenotyping of acute respiratory distress syndrome (ARDS) could be useful for evaluating the severity of ARDS or predicting its responsiveness to given therapeutic strategies, but no studies have yet investigated the heterogeneity of patients with severe ARDS requiring veno-venous extracorporeal membrane oxygenation (V-V ECMO). Methods We conducted this retrospective multicenter ...
- Blood pressure and acute kidney injury - Critical CareMaintaining the optimal blood pressure is an important aspect of preventing acute kidney injury (AKI), especially for vasopressor-dependent patients. Although mean arterial pressure (MAP) has played an important role in previous trials for prevention of AKI, there is little evidence that MAP actually reflects organ perfusion. In fact, several studies have suggested that perfusion pressure ...
- How I set up positive end-expiratory pressure: evidence- and physiology ...Driving pressure. C RS is proportional to the “baby lung” size []; therefore, as a good proxy of EELV (albeit possibly influenced by other factors, such as chest-wall compliance), C RS tends to increase with recruitment but decreases again once over-inflation begins.
- Lung ultrasound and ARDS: global collaboration is the way to goAbstract. We would like to extend our gratitude to Dr. da Hora Passos et al. for their interest in our recently published review and meta-analysis in Critical Care. In this response, we will elaborate on the points raised by the authors. We agree with the authors that LUS, like any other diagnostic technique, is valuable and safe only when ...
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