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Bookmark or Share- TOMM40 Gene - GeneCards | TOM40 Protein | TOM40 AntibodyTOMM40 (Translocase Of Outer Mitochondrial Membrane 40) is a Protein Coding gene. Diseases associated with TOMM40 include Cardiovascular System Disease and Alzheimer's Disease. Among its related pathways are Selective autophagy and Mitophagy.
- TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer’s Disease ...TOMM40 is essential for protein import into mitochondria. TOMM40 genetic variants are believed to increase the risk of Alzheimer’s disease (AD) in different populations. In this study, three exonic variants (rs772262361, rs157581, and rs11556505) and three intronic variants (rs157582, rs184017, and rs2075650) of the TOMM40 gene were ...
- Tom40: more than just a channel | Nature Structural & Molecular BiologyThe protein Tom40 is the main component of the outer membrane translocation machinery for mitochondrial preproteins. A new study extends the understanding of the molecular function of Tom40,...
- An increase in mitochondrial TOM activates apoptosis to drive retinal ...Intronic polymorphic TOMM40 variants increasing TOMM40 mRNA expression are strongly correlated to late onset Alzheimer’s Disease. The gene product, hTomm40, encoded in the APOE gene cluster, is...
- TOMM40, a risk gene for Alzheimer’s disease, is upregulated during ...TOMM40 gene has been associated with a risk of Alzheimer’s disease (Brabec et al., 2021). TOMM40 codes for the protein TOM40, which is the main channel forming protein for the translocase of outer membrane (TOM) in mitochondria.
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