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Bookmark or Share- Thrombotic Microangiopathy (TMA) - UNC Kidney CenterWhat is Thrombotic Microangiopathy (TMA)? Thrombotic Microangiopathy (often known simply as TMA) is a rare but serious medical disease. It is a pattern of damage that can occur in the smallest blood vessels inside many of your body’s vital organs – most commonly the kidney and brain.
- Thrombotic microangiopathies (including TTP, ST-HUS, and C-HUS)Thrombotic microangiopathy involves tiny clots forming within the microvasculature. This leads to erythrocyte fragmentation (which is termed MAHA: microangiopathic hemolytic anemia). Occlusion of the microvasculature also leads to tissue damage.
- Renal Thrombotic Microangiopathy: A Review - American Journal of Kidney ...Thrombotic microangiopathy (TMA) is a pathologic lesion characterized clinically by the presence of microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and ischemic organ injury. 1 The kidney is the most frequently injured organ, but other systems including the central nervous system, the cardiovascular and respiratory systems, and the g...
- T he - Mayo Clinic ProceedingsThrombotic microangiopathies (TMAs) comprise a heterogeneous set of conditions linked by a common histopathologic finding of endothelial damage resulting in microvascular thromboses and potentially serious complications.
- Syndromes of Thrombotic Microangiopathy | New England Journal of MedicinePrimary Thrombotic Microangiopathy (TMA) Syndromes. The presence of a causal abnormality, such as ADAMTS13 deficiency or a complement mutation, may not be clinically expressed until a...
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