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Bookmark or Share- Telomerase – Structure, Mechanism, Regulation, FunctionsTelomerase inhibition is a promising approach in cancer therapy, particularly for targeting cells with high telomerase activity. The mechanisms of inhibiting telomerase involve various strategies aimed at disrupting its activity, targeting its components, or interfering with its associated proteins.
- Telomerase in Cancer: Function, Regulation, and Clinical TranslationHere we review the telomere-dependent and -independent functions of telomerase in cancer, as well as its potential as a biomarker and therapeutic target to diagnose and treat cancer patients.
- Biochemistry, Telomere And Telomerase - StatPearls - NCBI BookshelfTelomerase is a ribonucleoprotein structure comprising a functional RNA component and a catalytic reverse transcriptase component. The RNA component houses a template for the synthesis of telomeric DNA.
- Telomerase: structure, functions, and activity regulationTelomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and tumor cells. In human somatic cells proliferation potential is strictly limited and senescence follows approximat …
- Telomerase - WikipediaTelomerase, also called terminal transferase, [1] is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most eukaryotes.
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