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Bookmark or Share- Contact - Sobolevsky LabContact. If interested in applying to the lab, please send your inquiry, CV and publication list to: Dr. Alexander Sobolevsky. 650W 168th st., BB-513. New York, NY 10032. Phone: +1 212 305-4249.
- Structure and gating mechanism of the transient ... - Sobolevsky LabThis paper presents the first structures of TRPV3. TRPV3 is predominantly expressed in skin keratinocytes and is implicated in cutaneous sensation including thermo-sensation, nociception and itch, in addition to maintenance of the skin barrier, wound healing, and hair growth.
- Structural basis of temperature sensation by the TRP ... - Sobolevsky LabOur hypothetical two-step temperature-induced activation mechanism of TRPV3 is reminiscent of the activation mechanisms of TRPM8 and TRPV1, which exhibit two contrasting Q 10 values as well as entropy and enthalpy changes during transitional and stabilized channel gating 31-35.
- Team - Sobolevsky LabAlexander Sobolevsky – PI / Associate Professor. Dr. Sobolevsky graduated from Moscow Institute of Physics and Technology in 1996 and received his PhD in biophysics in 2000. Then he joined Dr. Lonnie Wollmuth lab at the SUNY at Stony Brook. In 2004 he joined Dr. Eric Gouaux lab at OHSU.
- Research - Sobolevsky LabIonotropic glutamate receptors (iGluRs) and transient receptor potential (TRP) channels research by Sobolevsky Lab in Columbia University Medical Center.
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