The definition of a regulated article is found at 7 CFR § 340.1. If your modified organism meets the definition of a regulated article and you plan to import it, move it interstate or release it into the environment, you will need to apply for an authorization (permit or notification) before proceeding with the activity. More @Wikipedia
Hover over any link to get a description of the article. Please note that search keywords are sometimes hidden within the full article and don't appear in the description or title.