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Human RecQ helicases in DNA repair, recombination, and replication
RecQ helicases are an important family of genome surveillance proteins conserved from bacteria to humans. Each of the five human RecQ helicases plays critical roles in genome maintenance and stability, and the RecQ protein family members are often referred to as guardians of the genome.
The structural and functional characterization of human RecQ4 ... - Nature
On the basis of homology to the ATPase core domain of the founding member in Escherichia coli (EcRecQ), five RecQ helicases have been identified in humans: RecQ1, BLM, WRN, RecQ4 and RecQ5.
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Alongside $RBLZ, the Rebel Satoshi ecosystem welcomes $RECQ – your key to unparalleled experiences within our Arcade and wider universe. Earn, spend, and trade as you navigate Merch, the NFT Marketplace and play inside the Rebel Satoshi Arcade.
RecQ helicases: multifunctional genome caretakers - Nature
One highly conserved group of DNA helicases is the RecQ family. Genetic defects in three of the five human RecQ helicases, BLM, WRN and RECQ4, give rise to defined syndromes associated with...
RecQ helicases: caretakers of the genome | Nature Reviews Cancer
RecQ helicases are considered to be 'caretaker' tumour suppressors that suppress neoplastic transformation through control of chromosomal stability.
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