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Bookmark or Share- RB1 Gene - GeneCards | RB Protein | RB AntibodyRB1 (RB Transcriptional Corepressor 1) is a Protein Coding gene. Diseases associated with RB1 include Retinoblastoma and Small Cell Cancer Of The Lung. Among its related pathways are Defective binding of RB1 mutants to E2F1, (E2F2, E2F3) and Regulation of activated PAK-2p34 by proteasome mediated degradation.
- Rb1 Gene - Functions, Mutations, and Clinical Implications - GeneticsThe Rb1 gene, also known as the retinoblastoma gene, is a tumor suppressor gene that plays a crucial role in regulating cell growth and preventing the development of cancer. The gene is located on chromosome 13 and encodes a protein called Rb1.
- Pan-cancer molecular analysis of the RB tumor suppressor pathway - NatureThe retinoblastoma tumor suppressor gene (RB1) plays a critical role in coordinating multiple pathways that impact cancer initiation, disease progression, and therapeutic responses.
- Retinoblastoma protein - WikipediaThe retinoblastoma protein (protein name abbreviated Rb or pRb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers. [5] One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide.
- Pathology Outlines - RB1Point mutations inhibits Rb1 and c-myc binding For thyroid neoplasms, follicular adenomas were usually positive, follicular and papillary carcinomas were usually negative ( Mod Pathol 2000;13:562 )
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