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Bookmark or Share- Protein design - WikipediaProtein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. [1] Proteins can be designed from scratch (de novo design) or by making calculated variants of a known protein structure and its sequence (termed protein redesign).
- Protein designer and structure solvers win chemistry NobelThis so-called de novo design relied on Rosetta looking through databases of known protein structures for bits of proteins that could be useful in a hypothetical, desired protein. Once Rosetta had proposed an amino acid sequence, Baker’s team would insert the DNA coding for that sequence into bacteria, which then could produce the desired ...
- De novo design of protein structure and function with RFdiffusionNature - Fine-tuning the RoseTTAFold structure prediction network on protein structure denoising tasks yields a generative model for protein design that achieves outstanding performance on a...
- UW biochemist wins Nobel Prize for using computers to design ... - KUOWDavid Baker at his lab at the UW Medicine Institute for Protein Design on Oct. 9, 2024. A biochemist at the University of Washington School of Medicine has won the Nobel Prize in Chemistry for his ...
- Work on protein structure and design wins the 2024 chemistry NobelWork on protein structure and design wins the 2024 chemistry Nobel. David Baker (left) figured out how to build new proteins. Demis Hassabis (middle) and John Jumper (right) developed an AI tool ...
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