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Bookmark or Share- Pathology Outlines - Adenocarcinoma overviewTerminology. Terminology of lung adenocarcinoma was significantly revised in the 2015 WHO classification (J Thorac Oncol 2015;10:1243) Discontinuation of the terms bronchioloalveolar carcinoma (BAC) and mixed subtype adenocarcinoma. Addition of adenocarcinoma in situ (AIS) as a preinvasive lesion to join atypical adenomatous hyperplasia.
- Pathology Outlines - Basaloid squamous cell carcinomaEssential features. Esophageal basaloid squamous cell carcinoma (BSCC) is a rare variant of SCC. Morphological differential diagnoses could include adenoid cystic carcinoma, neuroendocrine carcinoma (particularly small cell type), carcinosarcoma and epithelioid sarcoma. BSCC is not human papillomavirus (HPV) related and has a relatively poor ...
- Pathology Outlines - Diffuse mesothelioma (pleura)Expression of p40. Metastatic sarcomatoid carcinoma. Expression of claudin 4 might be helpful. Sarcoma (primary or metastatic) Lack of expression of keratin; Expression of lineage specific markers Presence of disease defining molecular alterations such as t(X;18) and rearrangements of SS18 gene. Metastatic carcinoma
- Pathology Outlines - Pleomorphic adenomaIt is proposed to be a phenomenon associated with surgical manipulation (Am J Surg Pathol 2012;36:1674) Other features that may be seen in pleomorphic adenoma include. Tyrosine crystal: dense amorphous eosinophilic floret shaped crystal. Increased cellularity: so called cellular pleomorphic adenoma.
- Squamous metaplasia - Pathology OutlinesRegarded as a form of atrophy (postmenopausal squamous atypia) Squamous cell carcinoma: Confused with squamous metaplasia extending into preexisting endocervical glands. Shows significant nuclear abnormalities. Epithelial nests showing irregular border, distinguishable from outline of preexisting endocervical glands and desmoplastic stromal ...
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