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Bookmark or Share- Oxycodone (oral route) - Mayo ClinicThese may be symptoms of opioid-induced hyperalgesia and allodynia. This medicine may cause adrenal gland problems. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
- Opioids: using them safely, and finding better ways to manage pain ...Opioid pain medications may offer relief from acute pain, but their use carries risks. Learn more about using opioids safely, recognizing opioid addiction, managing pain using other approaches, and related topics.
- How opioid use disorder occurs - Mayo ClinicBecause of the risk of opioid misuse, it's often hard to get your healthcare professional to raise your dose or renew your prescription. Some opioid users who believe they need a bigger supply find illegal ways to get opioids or start using heroin. Some street drugs are laced with contaminants or much more powerful opioids such as fentanyl.
- What are opioids and why are they dangerous? - Mayo ClinicOpioid medicines travel through the blood and attach to opioid receptors in brain cells. This blocks pain messages and can boost feelings of pleasure. When opioid medicines are dangerous. What makes opioid medicines effective for treating pain also can make them dangerous. At lower doses, opioids may make you feel sleepy.
- Opioid stewardship: What is it? - Mayo ClinicNaloxone quickly reverses opioid overdose but only for a short time. It may last only 30 to 90 minutes, and you may need to give repeat doses until emergency services arrive. Give naloxone even if you aren't sure the person is having an opioid overdose. If you're taking an opioid, you should have naloxone with you when possible.
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