noun. neph· ew ˈne- (ˌ)fyü. chiefly British - (ˌ)vyü. plural nephews. 1. : a son of one's brother, sister, brother-in-law, or sister-in-law. 2. obsolete : a lineal (see lineal sense 3) descendant. especially : grandson. Examples of nephew in a Sentence. Recent Examples on the Web. More @Wikipedia
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