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Bookmark or Share- Pathology Outlines - Adenocarcinoma-small intestineAdditional histologic characterizations include mucinous adenocarcinoma (> 50% mucin), poorly cohesive cell carcinoma (with or without signet ring cells), medullary carcinoma, adenosquamous carcinoma (squamous and adenocarcinoma components), undifferentiated carcinoma or mixed neuroendocrine nonneuroendocrine neoplasm (MiNEN)
- Pathology Outlines - Squamous metaplasiaSquamous metaplasia is a replacement of urothelium with stratified squamous epithelium. There are 2 subtypes: nonkeratinizing (vaginal) and keratinizing
- Pathology Outlines - Well differentiated neuroendocrine tumorMixed neuroendocrine nonneuroendocrine neoplasms (MiNEN): Typically, neuroendocrine component is mixed with a ductal adenocarcinoma, occasionally with acinar cell carcinoma Each component must account for > 30% of the tumor Metastatic neuroendocrine tumors of other origin: Negative for islet 1, PAX6, PDX1
- Mixed neuroendocrine nonneuroendocrine neoplasmColonic MiNEN represents 11.2% of all gastroenteropancreatic tract MiNEN (World J Gastroenterol 2019;25:5991) In the colon, the rectosigmoid / sigmoid colon is more frequent than the ascending / transverse colon, cecum or ileocecal valve ( Case Rep Otolaryngol 2020;2020:5927610 )
- Pathology Outlines - AdenocarcinomaBladder, ureter & renal pelvis - Adenocarcinoma: defined as carcinoma derived from the urothelium and showing pure glandular differentiation; not including urachal adenocarcinoma or urothelial carcinoma with glandular differentiation
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