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Melittin treatment attenuates inflammation and stimulates the signaling for cell survival in the spleen and lung in an animal model of ALS [42]. Administration of melittin suppresses the expression of CD14 and Iba-1 (inflammatory proteins) in the lung of symptomatic ALS transgenic mice. More @Wikipedia
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- Anti-Inflammatory Applications of Melittin, a Major Component of Bee ...Melittin treatment attenuates inflammation and stimulates the signaling for cell survival in the spleen and lung in an animal model of ALS [42]. Administration of melittin suppresses the expression of CD14 and Iba-1 (inflammatory proteins) in the lung of symptomatic ALS transgenic mice.
- Bee Venom: Potential Benefits and Side Effects - HealthlineMelittin — a compound that consists of 26 amino acids — comprises about 50% of the dry weight of the venom. According to this 2017 study and this 2023 review of studies, melittin has been shown...
- Melittin Inhibits Colorectal Cancer Growth and Metastasis by Ac ... - MDPIMelittin has previously been found to have a positive effect on colorectal cancer (CRC) treatment, one of the most difficult-to-treat malignancies, but the mechanism by which this effect occurs remains unclear. We evaluated melittin’s pro-apoptotic and anti-metastatic effects on CRC in vitro and in vivo. The results showed that melittin-induced mitochondrial ROS bursts decreased ΔΨm ...
- Melittin: from honeybees to superbugs | Applied Microbiology and ...As a major component in the venom of European honeybee Apis mellifera, melittin has a great potential in medical applications. In this mini-review, we summarize a multitude of studies on anti-bacterial effects of melittin against planktonic and biofilm-embedded bacteria.
- Melittin, the Major Pain-Producing Substance of Bee Venom - SpringerMelittin is a basic 26-amino-acid polypeptide that constitutes 40–60% of dry honeybee (Apis mellifera) venom. Although much is known about its strong surface activity on lipid membranes, less is known about its pain-producing effects in the nervous system.
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