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- Opioids - IV / injecting Loperamide | Bluelight.orgIt is actually a myth that loperamide does not cross the blood brain barrier. It does, most of it is just usually pumped back out into non–CNS circulation by P-glycoprotein. You can use substances or foods that inhibit P-glycoprotein to keep it in the brain or take very high doses of loperamide. I would never personally attempt to IV it, but ...
- Opioids How much Loperamide... - Bluelight.orgCardiac issues like long QT syndrome and Torsades de Pointes can develop due to the Loperamide interfering with your body's hERG system or pacemaking abilities that control your heart at supra therapeutic doses. Other problems like Nystagmus can develop along with dizziness that is unpleasant to put it mildly.
- Getting loperamide across the blood-brain barrier - Bluelight.organtagonist, against loperamide in the guinea pig ileum was 3.83 nM, and in the mouse vas deferens was 82.87 nM indicating that loperamide in the guinea pig ileum acts on mu receptors while in the mouse vas deferens on another opiate receptor. PMID: 6319884, UI: 84116593 morpheus (Hive Bee) 08-29-02 02:50 No 350368 Not shit Bookmark
- Opioids - Loperamide (Imodium) Megathread v. 2 | Bluelight.orgBluelighter. Loperamide is an opioid drug used against diarrhea resulting from gastroenteritis or inflammatory bowel disease. In most countries it is available generically and under brand names such as Lopex, Imodium, Dimor, Fortasec, Lopedium, Gastro-Stop and Pepto Diarrhea Control. Loperamide is an opioid-receptor agonist and acts on the μ ...
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