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Bookmark or Share- Allergies explained - DermNetAllergy is an abnormal response of the body to a foreign body, known as an antigen. It involves the immune system recognising this antigen and mounting one of four types of response, which are detailed below. Allergy is also known as a ‘ hypersensitivity reaction’ or a ‘hypersensitivity response’. This article uses the terms allergy and ...
- Immunoglobulin E tests - DermNetImmunoglobulin E (IgE) is an antibody produced during a type I hypersensitivity reaction to an allergen. (See DermNet's page Allergies explained.) A schematic for the type I reaction pathway is shown below [1]. IgE antibodies are normally found in small amounts in the blood. A higher level than normal infers an allergic disorder may be present [2].
- Guidelines for the diagnosis and assessment of eczema - DermNetMost patients have elevated serum immunoglobulin (IgE) levels and a personal or immediate family history of atopy (type I allergies, allergic rhinitis, and asthma). Diagnosis. The diagnosis of eczema is based on patient history and clinical/physical examination. Features to consider when making a diagnosis are summarized in the following tables.
- Urticaria (Hives): a complete overview - DermNetAvoidance of relevant type 1 (IgE-mediated) allergens clears urticaria within 48 hours. Treat identified chronic infections such as H. pylori. Avoid aspirin, opiates and nonsteroidal anti-inflammatory drugs (paracetamol is generally safe). Minimise dietary pseudoallergens for a trial period of at least three weeks.
- Atopy Explained - DermNetAtopy refers to the genetic predisposition of experiencing an exaggerated immune response to allergens via the overproduction of immunoglobulin E (IgE). The term is derived from the Greek word meaning “the state of being out of place”. The atopic triad typically consists of atopic dermatitis (skin), asthma (airways), and allergic rhinitis ...
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