Definition of hamper. as in to hinder. to create difficulty for the work or activity of fallen branches hampered the hikers as they made their way along the narrow path. Synonyms & Similar Words. Relevance. hinder. impede. obstruct. embarrass. handicap. inhibit. delay. restrain. stymie. disrupt. interfere (with) constrain. block. cramp. hobble. More @Wikipedia
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