- • ISUP Grade 1(Gleason 3+3) and Grade 2 (Gleason 3+4) and Grade 1 (Gleason 3+3, with PSA≥10, or stage ≥ T2b) - Estimated life expectancy is ≥ 10 years - Candidate for primary curative therapy (Radical prostatectomy or radiation) if cancer progresses. More @Wikipedia
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