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Bookmark or Share- Gain-of-function research - WikipediaGain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect.
- The shifting sands of ‘gain-of-function’ research - NatureGain of function might result in bacteria that are extra sensitive to potassium ions 5, for example, or an Arabidopsis plant with short stems and curly leaves 6. A complementary approach —...
- What is 'gain-of-function' and why does it matter in the search for ...What does gain of function mean? Any organism can acquire a new ability or property, or "gain" a "function." This can happen through natural selection or a researcher's experiments.
- Gain-of-Function Research: Background and AlternativesTYPES OF GAIN-OF-FUNCTION (GOF) RESEARCH. Subbarao explained that routine virological methods involve experiments that aim to produce a gain of a desired function, such as higher yields for vaccine strains, but often also lead to loss of function, such as loss of the ability for a virus to replicate well, as a consequence.
- Gain-of-function research is more than just tweaking risky viruses – it ...The term “gain of function” is often taken to refer to research with viruses that puts society at risk of an infectious disease outbreak for questionable gain.
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