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Bookmark or Share- Targeting Erbin in B cells for therapy of lung metastasis of colorectal ...Our study uncovered a key role of Erbin in regulating PD1 + IgA + B cells in lung metastasis of CRC. Targeting Erbin as well as combined use of neutralizing B cells and antibodies neutralizing...
- Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes ...Targeting Erbin in platelets/MKs by a nanovesicle system dramatically attenuated lung metas-tasis in mice . Our study identifies an Erbin-mitochondria axis in platelets/MKs, which suppresses B. in vivo. cell-mediated antitumor immunity, suggesting a new way for the treatment of metastasis.
- ERBIN Gene - GeneCards | ERBIN Protein | ERBIN AntibodyERBIN (Erbb2 Interacting Protein) is a Protein Coding gene. Diseases associated with ERBIN include Autosomal Dominant Combined Immunodeficiency Due To Erbin Deficiency and Immunodeficiency 35. Among its related pathways are Resistance of ERBB2 KD mutants to sapitinib and Signaling by ERBB2 KD Mutants.
- ERBIN: a basolateral PDZ protein that interacts with the ... - NatureERBIN contains 16 leucine-rich repeats (LRRs) in its amino terminus and a PDZ (PSD-95/DLG/ZO-1) domain at its carboxy terminus, and belongs to a new PDZ protein family.
- Erbin (protein) - WikipediaErbb2 interacting protein (ERBB2IP), also known as erbin, is a protein which in humans is encoded by the ERBB2IP gene. [5] Discovered in 1997, erbin is a 200kDa protein containing a PDZ domain. [6]
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