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Bookmark or Share- Differential diagnosis of vulval ulcers - DermNetPrimary chancre of syphilis. There is a single, painless ulcer with a clean base and firm raised edges. It is often associated with large, non-tender inguinal lymph nodes. Lymphogranuloma venereum. There is a single, transient, painless ulcer. It is often associated with urethritis and followed by tender inguinal lymph nodes weeks later ...
- Syphilis - DermNetUntreated, 25% of patients develop secondary syphilis within three months (average six weeks) after the initial chancre. Syphilis is a multisystem infection and the patient is very infectious during this stage. Systemic symptoms may include fever, headache, malaise, myalgia, arthralgia, and lymphadenopathy.
- Skin conditions and HIV/AIDS: A Complete Overview - DermNetThe presence of a chancre may present an increased ability to transmit HIV via sexual contact. Bacillary angiomatosis is a less common infection, typically seen in immunocompromised patients only. It is caused by two Bartonella bacteria species and presents as a papulonodular rash, with hyperpigmented red or purple lesions.
- Syphilis pathology - DermNetSyphilis is an infectious disease caused by the spirochaete Treponema pallidum.. Histology of syphilis. Primary syphilis (primary chancre) demonstrates an acanthotic epidermis which erodes with time to become ulcerated.
- African trypanosomiasis - DermNetThe chancre is an indurated (hardened) red or purple nodule, 2 to 5 cm in diameter, which is accompanied by enlarged lymph nodes. A central necrotic eschar (dark-coloured crust) may form before the chancre desquamates (peels off in scales) within 2 to 3 weeks, leaving no trace.
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