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Bookmark or Share- Long genetic and social isolation in Neanderthals before ... - Cell PressNeanderthal genomes have been recovered from sites across Eurasia, painting an increasingly complex picture of their populations’ structure that mostly indicates that late European Neanderthals belonged to a single metapopulation with no significant evidence of population structure.
- Issue: Cell GenomicsIn this issue of Cell Genomics, Djeddi et al. uncover how airway epithelial cells, when activated by rhinovirus, influence genetic susceptibility to childhood-onset asthma, and this preview emphasizes the need to address these missing regulatory effects across diverse cell states.
- Gene expression and RNA splicing explain large proportions ... - Cell PressHerein, we address the contribution of regulatory variants to mammalian complex traits with a comprehensive analysis of cattle data. We mapped eQTLs and sQTLs from transcriptomic data across 16 tissues in more than 40 breeds from 4,725 cattle, comprising between 105 and 945 individuals (average 295) per tissue.
- OpenPBTA: The Open Pediatric Brain Tumor Atlas: Cell Genomics - Cell PressThrough the OpenPBTA, we present a comprehensive, collaborative, open genomic analysis of 1,074 tumors and 22 cell lines, comprised of 58 distinct brain tumor histologies from 943 patients.
- New articles: Cell GenomicsUeda et al. discover that changes in transcript isoforms can alter the function of immune response genes in human B cells. These changes help explain how the body fights infections and regulates the immune system, emphasizing the role of gene splicing in health and disease.
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