Answer From Sheldon G. Sheps, M.D. Yes. Weight gain is a side effect of some beta blockers. The average weight gain is about 2.6 pounds (1.2 kilograms) over six or more months. You're more likely to gain weight with older beta blockers, such as atenolol (Tenormin) and metoprolol (Lopressor, Toprol-XL). The weight gain tends to happen in the ... More @Wikipedia
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