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Bookmark or Share- Notes from the Field - Centers for Disease Control and Preventionacid (PAS), linezolid, clofazimine, and bedaquiline. Given the limited treatment options, the patient began a regimen of beda - quiline, clofazimine, linezolid, PAS, and cycloserine. In light of the extensively drug-resistant (XDR) disease and potential for limited drug tolerability, inclusion of delamanid, which is not
- Xpert MTB/RIF Assay | Tuberculosis (TB) | CDCThe Xpert MTB/RIF assay is a test that simultaneously detects Mycobacterium tuberculosis complex (MTBC) and resistance to rifampin (RIF), one of the most effective drugs used to treat tuberculosis (TB).
- Clinical Overview of Drug-Resistant Tuberculosis DiseaseProvisional CDC Guidance for the Use of Pretomanid as part of a Regimen [Bedaquiline, Pretomanid, and Linezolid (BPaL)] to Treat Drug-Resistant Tuberculosis Disease CDC's guidance on BPaL administration, precautions and adverse event monitoring, and more.
- Provisional CDC Guidance for the Use of Pretomanid as part of a Regimen ...Additionally, while the initial FDA approval for bedaquiline in 2012 for MDR TB included a treatment duration of 24 weeks, based on the Nix-TB trial, when given as part of the BPaL regimen, bedaquiline should be administered for 26 weeks 9. Treatment with BPaL can be extended to 9 months (39 weeks) based on clinical, radiographic, or ...
- Tuberculosis Trials Consortium | Tuberculosis (TB) | CDCThe trial compares the effectiveness and safety of new 4-month bedaquiline, moxifloxacin, and pyrazinamide-based regimens to the standard of care 6-month regimen for TB disease. ClinicalTrials.gov Identifier: NCT05766267; ASTERoiD/Study 37
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