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Bookmark or Share- Women in science: Q&A with Martha Grogan, M.D.With researchers Marina Ramirez-Alvarado, Ph.D. and Angela Dispenzieri, M.D., Dr. Grogan co-leads the Mayo Amyloid Team, a leader in amyloidosis research and treatment. Dr. Grogan's areas of clinical research include studies analyzing diagnostic imaging, treatment and outcomes for patients with cardiac amyloidosis.
- What is amyloidosis and 10 signs you might have itAmyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a substance called amyloid builds up in your organs. Amyloid is an abnormal protein that is produced in your bone marrow and can be deposited in any tissue or organ. Amyloidosis frequently affects the heart, kidneys, liver, spleen, nervous system and digestive tract. It is often […]
- Mayo Clinic Researchers Find Way to Prevent Accumulation of Amyloid ...JACKSONVILLE, Fla. — Mayo Clinic researchers led a laboratory study that found a new way to prevent the accumulation of amyloid plaque – a key feature of Alzheimer’s disease – by eliminating a class of molecules called heparan sulfates that form on brain cells. “Just as a carpet covers a floor and can hold dirt, molecules […]
- Spotlight on early detection of 3 heart diseases using ECG-AIAmyloidosis is a rare disease of misfolded proteins that go astray to form deposits of amyloid in organs, nerves and tissues. There are several different types, but when enough amyloid builds up in the heart , it causes heart failure and symptoms such as shortness of breath, fluid buildup and fainting.
- Blood clots in the heart are common in patients with COVID-19Of note, more than 26% of patients with COVID-19 who were studied were found to have cardiac amyloidosis ― a cohesive buildup of abnormal proteins that interferes with the heart's ability to function. This is a much higher rate than the 3.7% occurrence of cardiac amyloidosis typically found at autopsy in patients at Mayo Clinic.
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