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Bookmark or Share- Recurrent evolution and selection shape structural diversity at the ...Human genomes contain three different amylase genes located proximally to one another at a single locus: AMY1, which is expressed exclusively in salivary glands, and AMY2A and AMY2B, which are...
- Craving carbs? Blame an ancient gene. - Ars TechnicaThe salivary amylase gene, known as AMY1, is already known to have helped us adapt to eating carbs. It encodes amylase, an enzyme that breaks starches found in pasta and bread down to glucose ...
- Reconstruction of the human amylase locus reveals ancient ... - AAASAnalysis of archaic hominin genomes showed that some Neanderthals harbored AMY1 duplications. We also found that hunter-gatherers already had highly variable AMY1 copy numbers as early as 45,000 years ago, followed by a significant increase in the AMY1 copy number in the genomes of European farmers over the past 4000 years.
- The AMY1 Gene Variation from Our Ancient Ancestors May Explain Our ...A study of a gene key to breaking down carbohydrates started duplicating itself in humans over 800,000 years ago— well before the dawn of agriculture. A team of researchers report in Science that the gene, called AMY1, started creating variations of itself long before humans split from neanderthal. It plays an essential role in producing ...
- Structural forms of the human amylase locus and their ... - NatureOne such region contains the three amylase genes (AMY2B, AMY2A and AMY1) responsible for digesting starch into sugar. Copy number of AMY1 is reported to be the largest genomic influence on...
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