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Bookmark or Share- Best AlphaFold Posts - RedditSeems like DeepMind just caused the ImageNet moment for protein folding. Blog post isn't that deeply informative yet (paper is promised to appear soonish). Seems like the improvement over the first version of AlphaFold is mostly usage of transformer/attention mechanisms applied to residue space and com
- AlphaFold3 was just announced : r/bioinformatics - Reddit"we describe our AlphaFold 3 model with a substantially updated diffusion-based architecture, which is capable of joint structure prediction of complexes including proteins, nucleic acids, small molecules, ions, and modified residues" the possibilities are endless Too excited to see how it will change the structural bioinformatics
- So what has the consequences so far been of AlphaFold?Drug development takes decades, even if alphafold does all it was promised to it's gonna take years before it creates viable drugs, and thats not even considering pharmaceutical companies having to rewrite lots of their software stack to incorporate it. But in the meantime check out unfolded from the deepmind youtube channel.
- How important of a breakthrough is DeepMind's AlphaFold?Alicecomma. • 3 yr. ago. The problem with AlphaFold is it's trained on a limited set of known data, specifically annotated data where a large number of similar structures exist. It sucks at predicting membrane proteins and some barrel proteins I fed it, as the active sites tend to be cocked up to the point where it can't fit known substrates.
- Announcing AlphaFold 3: our state-of-the-art AI model for ... - RedditYes, AlphaFold has been involved in several recent medical breakthroughs and advancements: Accelerating drug discovery for neglected diseases: The Drugs for Neglected Diseases Initiative (DNDi) is using AlphaFold to help identify new drug candidates for diseases like Chagas disease and leishmaniasis that disproportionately affect developing ...
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