Synonym for Take a guess Take a guess. Make a guess. What's your best guess? You can also say "Can you guess?" or "Go on, guess!" They all mean exactly the same thing. They're all used commonly except "make a guess". That is said sometimes, but it's not common.|@LeeKevin My own take on this (not supported by anything) is that “take a guess” is a way of arriving at a response (i.e., by ... More @Wikipedia
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