In a 5-1 loss to Seattle on Friday night — Oakland's 10th in 11 games — the bright spot was Zach Neal, who retired all 15 batters he faced to become just the second reliever in club history to pitch at least five perfect innings. Neal came on with one aboard in the third after starter Raul Alcantara (1-3) was tagged for five runs on four homers — including two by Robinson Cano — in two-plus innings. Evan Scribner, Nick Vincent and Steve Cishek each pitched a scoreless inning of relief. Cano drove a 1-1 pitch over the wall in center to give the Mariners to a 2-0 lead in the first after a leadoff infield single by Aoki. Aoki made it 3-0 in the second with his fourth homer just inside the right field foul pole. The A's loaded the bases in the fifth on two walks and a two-out error by second baseman Cano, but Walker retired Stephen Vogt on a popout. Horn has spent 39 years as an athletic trainer in the Athletics' organization, including the last nine seasons with the major league club. Rookie RHP Jharel Cotton (2-0, 1.44 ERA) makes his fifth career start since being called up from Triple-A Nashville on Sept.