Stephanie Zito | (TNS) Bankrate.com Key takeaways —Trip cancellation and interruption insurance reimburses travelers for prepaid expenses when their trip is canceled or interrupted due to circumstances beyond their control. —This coverage only applies in specific situations such as illness, injury, natural disasters or financial defaults by travel providers. —Optional coverage options, such as “cancel for any reason” or “interrupt for any reason” insurance, can provide more flexible coverage but come with a higher cost. —Many top travel credit cards include trip cancellation and interruption insurance as a cardholder perk. Whether you get travel insurance through a policy you purchase or from a travel credit card, you’ve probably noticed that most plans include a trip cancellation and interruption insurance benefit. This perk is one of the most common travel insurance benefits and also one of the most valuable.