Comment on Frozen mammoth skin retained its chromosome structure

Frozen mammoth skin retained its chromosome structure

Enlarge (credit: LEONELLO CALVETTI/SCIENCE PHOTO LIBRARY) One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we've worked with, these fragments scatter and mix with contaminants, making reconstructing a genome a large technical challenge. But a dramatic paper released on Thursday shows that this isn't always true.

 

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