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Shares in the pharmaceutical company fell a staggering 85% on Monday after it reported disappointing Phase 3 results, but its problems started way before that. In March, pharmaceutical company Cassava Sciences made headlines for a report by the Food and Drug Administration (FDA) that cast doubt on the positive trial results of its novel Alzheimer’s drug, simufilam.

What makes it different from other AI technologies is its ability to take in and modify existing audio—for example, by taking a line played on a piano and transforming it into a line sung by a human voice. Nvidia on Monday showed a new artificial intelligence model for generating music and audio that can modify voices and generate novel sounds — technology aimed at the producers of music, films and video games.

Trump’s team insists he can make the math work. Donald Trump has big plans for the economy — and a big debt problem that will be a hurdle to delivering on them. Trump has bold ideas on tax cuts, tariffs and other programs, but high interest rates and the price of repaying the federal government’s existing debt could limit what he’s able to do.

The production and use of plastics globally is set to reach 736 million tons by 2040, up 70% from 2020. Negotiators gathered in Busan, South Korea, on Monday in a final push to create a treaty to address the global crisis of plastic pollution. It’s the fifth time the world’s nations convene to craft a legally binding plastic pollution accord.

In a new book, Auden Schendler talks about his time at Aspen Skiing Company and how they convinced Kimberly-Clark to use more sustainable materials. One day in the early part of my career at Aspen Skiing Company, I was sitting at my desk and the phone rang. It was a group called Forest Ethics (I’d never heard of it), which was working with Greenpeace on a boycott of Kimberly-Clark.