Comment on Placebo’s troublesome cousin nocebo: Does telling patients of possible side effects make them more likely?

Placebo’s troublesome cousin nocebo: Does telling patients of possible side effects make them more likely?

Patients who are told their medication can have certain side effects may report these symptoms more often than patients who aren’t aware their treatment carries these risks, a study of popular cholesterol pills suggests.Researchers focused on what they dubbed the “nocebo” effect, or the potential for people to complain of treatment-related side effects when they think they’re taking a specific drug but are actually given a placebo, or dummy pill, without any active ingredients.“It has been recognized for many years that when patients are warned about possible adverse reactions to a drug, they are much more likely to complain of these side effects than when they are unaware of the possibility that such side effects might occur,” said senior study author Dr.

 

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