Organ and tissue donation are not popular topics of conversation. It’s hard to discuss or even consider end-of-life care with loved ones, but it’s an important issue that has the potential to save many lives: In 2015 alone, 30,973 organ transplants were reported in the U.S. With an 80-90 percent success rate, that means organ donation saves a lot of lives every year. Organ donation typically follows two paths: In the first, the donor is pronounced clinically dead or brain dead.