When Ribosomes Go Rogue

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed certain cancers or were surprisingly resistant. The team spotted a peculiar litter in which some baby mice had short, kinked tails and misplaced ribs growing out of their neck bones.

BING NEWS:
  • Cancer Hijacks Proteins to Hide from Immune System
    The proteins Faller and colleagues describe are known as ribosomes. These are intercellular molecules responsible for the generation of proteins and can be found throughout the cell body with a ...
    10/24/2024 - 2:30 am | View Link
  • When ribosomes go rogue
    Unusual variations in the cellular protein factory can skew development, help cancer spread and more. But ribosome variety may also play biological roles, scientists say.
    10/23/2024 - 10:41 pm | View Link
  • An elegant switch regulates production of protein variants during cell division
    Our cells contain thousands of proteins that have gone largely undetected and unstudied until recent years: these are variants of known proteins, which cells can make when their protein-building ...
    10/23/2024 - 7:34 am | View Link
  • P-stalk ribosomes identified as key regulators of immune evasion in cancer
    Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer types. It offers new insights into post-translational mechanisms ...
    10/22/2024 - 6:06 pm | View Link
  • Cancer Cells Hijack Ribosomes to Escape the Immune System
    Cells change their ribosomes when they receive a danger signal from the immune system, the new study showed. “They change the balance toward a type of ribosome that has a flexible arm sticking out, ...
    10/22/2024 - 5:00 am | View Link
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BING SEARCH:
  • Ribosome
    Ribosomes (/ ˈraɪbəzoʊm, - soʊm /) are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA molecules to form polypeptide chains. Ribosomes consist of two major components: the small ...
    10/23/2024 - 4:31 am | View Website
  • 5.4: Ribosomes
    Electron microscopy has shown us that ribosomes, which are large complexes of protein and RNA, consist of two subunits, aptly called large and small (Figure 5.4.3 5.4. 3). Ribosomes receive their “orders” for protein synthesis from the nucleus where the DNA is transcribed into messenger RNA (mRNA).
    10/22/2024 - 9:29 pm | View Website
  • Ribosomes: Definition, Structure, & Functions, with Diagram
    What are ribosomes in biology, where are they found & what do they do: facts, analogy, meaning, components, structure, & purpose with examples, & labeled picture.
    10/22/2024 - 5:33 pm | View Website
  • Ribosome | Definition, Function, Formation, Role, Importance, & Facts ...
    ribosome, particle that is present in large numbers in all living cells and serves as the site of protein synthesis. Ribosomes occur both as free particles in prokaryotic and eukaryotic cells and as particles attached to the membranes of the endoplasmic reticulum in eukaryotic cells.
    10/22/2024 - 4:14 pm | View Website
  • Ribosome
    A ribosome is a complex cellular mechanism used to translate genetic code into chains of amino acids. Long chains of amino acids fold and function as proteins in cells.
    10/22/2024 - 3:02 pm | View Website
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