MSN has debuted the new trailer for Columbia Pictures' Angels & Demons , opening in theaters on May 15th. Directed by Ron Howard, the suspense thriller stars Tom Hanks, Ewan McGregor, Ayelet Zurer, Stellan Skarsgard, Pierfrancesco Favino, Nikolaj Lie Kaas and Armin Mueller-Stahl. The film is based upon the bestselling novel by Dan Brown.