Image source: StockMonkeys.com, via Flickr.Opko Health's (NASDAQ: OPK) CEO Phillip Frost isn't shy when it comes to deal-making. Throughout his career, he's focused considerable attention on growing companies via acquisition, and that's turned him into one of healthcare's richest entrepreneurs. At Opko Health, Frost has already orchestrated a slew of deals that have pumped up the company's pipeline and expanded it into specialty testing.