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Bookmark or Share- BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer InstituteEvidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks associated with BRCA1/BRCA2, screening, risk-reduction, treatment, and prognosis.
- PALB2 and Associated Cancer Risks (PDQ®) - NCI - National Cancer InstituteThe Breast Cancer Association Consortium (BCAC) sequenced 34 suspected breast cancer susceptibility genes in 60,466 women with invasive breast cancer and 53,461 controls to refine estimates for breast cancer risk.
- Genetic Testing Fact Sheet - NCI - National Cancer InstituteClinical practice guidelines recommend genetic testing for anyone diagnosed with triple-negative breast cancer, ovarian cancer, pancreatic cancer, colorectal cancer before age 50, metastatic prostate cancer, or male breast cancer. For people with these cancers, knowing whether their cancer is related to an inherited harmful genetic change may ...
- The Genetics of Cancer - NCI - National Cancer InstituteGenetic tests can help families with a history of breast and ovarian cancer make screening and treatment decisions. Not everyone needs to get genetic testing for cancer risk. Your doctor or health care provider can help you decide if you should get tested for genetic changes that increase cancer risk.
- BRCA Gene Changes: Cancer Risk and Genetic TestingPeople who inherit a harmful change (also called a mutation or pathogenic variant) in one of these genes have increased risks of several cancers—most notably breast and ovarian cancer, but also several other types of cancer (1, 2).
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