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A gunman walked into a business school in downtown St. Louis on Tuesday and shot an administrator in the chest before shooting himself, police said.

A 30-year-old woman suspected of abandoning her infant son last week in an apartment building in St. Louis was found dead in the trunk of her car, prompting the police chief in a nearby town to stand on a street corner soliciting reward money for the hunt for her killer.

In a modest milestone for President Barack Obama's high-speed rail vision, test runs started zooming along a small section of the Amtrak line between Chicago and St. Louis at 111 mph Friday.

The rocker and noted gun enthusiast is stirring up attention after comments he made about President Obama and his administration at a National Rifle Association conference in St. Louis over the weekend.

"I was not sure I was going to live," says Derrik Sweeney after arriving in St. Louis. He and two others had been arrested in Cairo and accused of throwing firebombs. Three American college students detained for several days in Egypt as deadly protests swept Cairo have flown home to freedom, one describing an ordeal so terrifying he wasn't sure he would survive it.

Gov. Jay Nixon announced he had declared a state of emergency, allowing state agencies to assist local jurisdictions with their emergency responses to the storm's aftermath, including the destruction at the airport.St.

A suburban St. Louis high school teacher who appeared in a series of adult films in the mid-1990s has been placed on leave after informing administrators ...

Washington University in St. Louis has been given one of the largest gifts in its history, The Chronicle of Higher Education reports.

The mayor of a decaying village near St. Louis known for its strip clubs and beset by financial troubles and embezzlements was gunned down early Thursday, and police say his killer is still out there.

Three women were shot to death in East St. Louis as they sat in a car with two children.