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The Houston Texans have put themselves in a position to be the NFL's first team to seal a spot in the playoffs and to move a step closer toward earning home-field advantage in the AFC....

Peyton Manning had no trouble clearing those two interceptions out of his head and leading a fourth-quarter comeback....

Notre Dame’s impressive win on the road against Oklahoma Saturday meant the Irish should be considered BCS championship contenders with just a month or so left in this 2012 college football regular season. Confirmation of that was unveiled Sunday night in the latest BCS standings when the Irish, previously ranked No. 5 in the BCS, jumped up two spots to take the No. 3 ranking.

The New York Jets appeared inept in all phases in a 30-9 loss to the Miami Dolphins, and even though Tim Tebow didn't throw a pass, he may have been to blame for an early letdown.

The San Francisco 49ers sit alone atop the NFC West for now – hardly the kind of firm hold on the division they owned last October. Alex Smith threw a 12-yard touchdown pass to Delanie Walker late in the third quarter and San Francisco held off the Seattle Seahawks 13-6 on Thursday night as the 49ers won their long-awaited division opener.

All the single ladies will be watching the upcoming Super Bowl along with football lovers. That's because Beyonce is the halftime show performer....

For Pro Football Hall of Famer Charlie Sanders, the stories and memories of his late teammate Alex Karras will never go away. They’ve always made Sanders smile. They’ll always make him laugh. “Alex was really a gentleman inside, but he had that aura about him that said he had to be tough,” Sanders said. “It’s sad that we talk about it at this particular time, but it’s good to remember.”

Colts owner Jim Irsay confirmed on Monday morning that head coach Chuck Pagano is hospitalized with leukemia, but Irsay said the cancer is treatable and that everyone is optimistic. “It’s been a very difficult week,” Irsay said. “The coach was feeling some fatigue over the last two weeks, had noticed some bruising on his body that at first he thought could have been from contact on the field, coaching, or playing with his grandkids or whatever, and eventually through talking to his wife, Tina, she said, ‘You need to check that out.’”

NFL officials ended their labor dispute with the league by approving a new eight-year contract with a 112-5 vote Saturday, then hustled off to the airport to get to work. Next stop, stadiums around the country. And, the officials hope, anonymity.

The National Football League (NFL) reached an agreement to end a labor dispute with its regular game officials on Wednesday, ending three weeks of questionable calls that had threatened the integrity of the sport.