The legislative committee tasked with helping to guide Colorado’s response to substance use has reconvened for the first time in four years to face a drastically changed drug landscape, a worsened overdose crisis and a series of worrisome data points about the state’s patchwork treatment system. The Opioid and Other Substance Use Disorders Study Committee — featuring six Democrats and four Republicans from the state legislature — met for the first time Thursday and will meet again over the coming months with the goal of forwarding potential bills to the full General Assembly when it reconvenes in January. The group had met for three straight years through 2019, but COVID-19’s emergence derailed its schedule.