Backers claim it can ease pain and inflammation, aid blood flow and weight loss, improve skin and even ward off aging and depression. Las Vegas police and Nevada state officials have opened investigations into the circumstances involving the death, but it has moved slowly because the industry is so new in the state that no one agency assumed responsibility for it. California officials said its industrial relations and consumer affairs departments and state medical board have no oversight of the practice, calling it an experimental and alternative treatment unsupported by evidence. Given that the coldest temperature ever recorded on Earth was minus-128 degrees Fahrenheit, experts say the health impacts of cryotherapy can't be predicted without more research. The FDA said in a statement it would regulate any device if a manufacturer makes medical claims such as reducing muscle soreness, shortening injury recovery time or increasing blood circulation, but not if the claims are non-medical and involve such things as comfort, soothing or relief. Eric Rauscher, founder of Dallas-based distributor CryoUSA, said the company supports some form of regulation and specifically trains buyers of the machines not to make medical claims.