Enlarge (credit: Tondini, Isidro, Camarós, 2024.) The 4,000-year-old skull and mandible of an Egyptian man show signs of cancerous lesions and tool marks, according to a recent paper published in the journal Frontiers in Medicine. Those marks could be signs that someone tried to operate on the man shortly before his death or performed the ancient Egyptian equivalent of an autopsy to learn more about the cancer after death. “This finding is unique evidence of how ancient Egyptian medicine would have tried to deal with or explore cancer more than 4,000 years ago,” said co-author Edgard Camarós, a paleopathologist at the University of Santiago de Compostela.