Five people were sent to the hospital Wednesday morning after a two-vehicle crash in Aurora, police said. One of the cars ran a red light and crashed into the other, the Aurora Police Department said in a statement on social media. The car may also have been speeding. Around 2 a.m. Wednesday, Aurora officers responded to reports of a crash near East 40th Avenue and Peña Boulevard, police said. Paramedics took five unidentified adults to the hospital — two with serious or life-threatening injuries and three with minor injuries — police said. The crash shut down all lanes of East 40th Avenue and Peña Boulevard for multiple hours Wednesday morning for the crash investigation and clean-up, police said. Related Articles Crashes and Disasters | Centennial construction worker killed after dump truck backed over him, police say Crashes and Disasters | Crash on I-25 near Alameda in Denver sends car careening into South Platte River Crashes and Disasters | One dead after fatal Denver crash early Tuesday morning Crashes and Disasters | One seriously injured during Aurora house fire Sunday night Crashes and Disasters | Southbound I-25 reopens in Denver after fatal crash As of 6:30 a.m., Peña Boulevard had reopened but East 40th Avenue remained closed. This is a developing story. Sign up to get crime news sent straight to your inbox each day.